Generic model for biological regulation

A substantial portion of molecules in an organism are involved regulation a wide spectrum biological processes. Several models have been presented for various forms regulation, including gene expression and physiological regulation; however, generic model is missing. Recently new unifying theory biology, poikilosis, was presented. Poikilosis indicates that all systems display intrinsic heterogeneity. The concept poikilosis allowed development applicable to types regulated systems. perturbation-lagom-TATAR countermeasures-regulator (PLTR) combines the effects perturbation lagom (allowed sufficient extent heterogeneity) system with tolerance, avoidance, repair, attenuation resistance (TARAR) countermeasures, possible regulators. There three modes two which lagom-related. In first scenario, maintained, both (passive) active TARAR countermeasures can be involved. second mode, there shift from one another. third reguland entity target regulatory shift, often irreversible or requires action another regulator return original state. After enters maintenance but at extent. described elaborated examples applications, medicine biology. Consequences non-lagom heterogeneity introduced, along novel idea therapy by reconstituting processes extent, even when primary effect cannot treated.